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2023\u5e745\u6708\uff0cEXTENTORCH\u7814\u7a76\u7684\u4e3b\u8981\u7ec8\u70b9\u8fbe\u5230\u65b9\u6848\u9884\u8bbe\u7684\u4f18\u6548\u8fb9\u754c\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u7531\u6b64\u6210\u4e3a\u5168\u7403\u9996\u4e2a\u5728ES-SCLC\u4e00\u7ebf\u6cbb\u7597III\u671f\u7814\u7a76\u4e2d\u8fbe\u6210\u603b\u751f\u5b58\u671f\uff08OS\uff09\u548c\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u53cc\u91cd\u4e3b\u8981\u7ec8\u70b9\u7684PD-1\u6291\u5236\u5242\u3002<\/p>\n\n\n\n

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\u541b\u5b9e\u751f\u7269\u5168\u7403\u7814\u53d1\u603b\u88c1\u90b9\u5efa\u519b\u535a\u58eb<\/strong>\u8868\u793a\uff1a\u201c\u5f88\u9ad8\u5174\u5728\u4eca\u5929\u89c1\u8bc1\u4e86\u7279\u745e\u666e\u5229\u5355\u6297\u7b2c10\u9879\u9002\u5e94\u75c7\u7684\u6210\u529f\u7533\u62a5\u3002\u81ea2015\u5e74\u5e95\u83b7\u51c6\u8fdb\u5165\u4e34\u5e8a\u4ee5\u6765\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u7784\u51c6\u4e2d\u56fd\u4e43\u81f3\u5168\u7403\u80bf\u7624\u60a3\u8005\u7684\u672a\u5c3d\u4e4b\u9700\uff0c\u5df2\u9646\u7eed\u5f00\u5c55\u4e86\u8d85\u8fc740\u9879\u6ce8\u518c\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5e76\u5728\u4e0d\u540c\u7624\u79cd\u4e2d\u8868\u73b0\u51fa\u7a33\u5b9a\u3001\u5f3a\u5927\u7684\u6297\u80bf\u7624\u6d3b\u6027\u3002\u5176\u4e2d\u4ec5\u80ba\u764c\u9886\u57df\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u5df2\u67093\u9879\u5927\u578bIII\u671f\u4e34\u5e8a\u7814\u7a76\u53d6\u5f97\u6210\u529f\uff0c\u8986\u76d6\u4e86\u4e0d\u540c\u4e9a\u578b\u548c\u75c5\u7a0b\u9636\u6bb5\u3002\u6211\u4eec\u5c06\u52aa\u529b\u63a8\u8fdb\u76f8\u5173\u9002\u5e94\u75c7\u7684\u4e0a\u5e02\u7533\u8bf7\u5de5\u4f5c\uff0c\u8ba9\u66f4\u591a\u80bf\u7624\u60a3\u8005\u80fd\u591f\u53d7\u76ca\u4e8e\u6211\u4eec\u7684\u521b\u65b0\u7597\u6cd5\uff01\u201c<\/p>\n\n\n\n

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\u3010\u53c2\u8003\u6587\u732e\u3011<\/h5>\n\n\n\n
1.    Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021 Feb 4.<\/h5>\n\n\n\n
2.     \u5f20\u723d\u7b49.\u5c0f\u7ec6\u80de\u80ba\u764c\u4e2a\u4f53\u5316\u6cbb\u7597\u8fdb\u5c55[J].\u4e2d\u56fd\u80bf\u7624\u4e34\u5e8a,2017,44(12):571-576.<\/h5>\n\n\n\n
3.     Gaspar LE, et al. Small-cell lung cancer: prognostic factors and changing treatment over 15 years. Clin Lung Cancer. 2012 Mar;13(2):115-22.<\/h5>\n\n\n\n
4.     Pesch B, et al. Cigarette smoking and lung cancer–relative risk estimates for the major histological types from a pooled analysis of case-control studies. Int J Cancer. 2012 Sep 1;131(5):1210-9.<\/h5>\n\n\n\n
5.     Kalemkerian GP. Small Cell Lung Cancer. Semin Respir Crit Care Med. 2016 Oct;37(5):783-796.<\/h5>\n\n\n\n
6.     Stinchcombe TE, et al. Limited-stage small cell lung cancer: current chemoradiotherapy treatment paradigms. Oncologist. 2010;15(2):187-95.<\/h5>\n\n\n\n
7.     Lally BE, et al. Small cell lung cancer: have we made any progress over the last 25 years? Oncologist. 2007 Sep;12(9):1096-104.<\/h5>\n\n\n\n
8.     Socinski MA, et al. Phase III study of pemetrexed plus carboplatin compared with etoposide plus carboplatin in chemotherapy-naive patients with extensive-stage small-cell lung cancer. J Clin Oncol. 2009 Oct 1;27(28):4787-92.<\/h5>\n\n\n\n

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\u5173\u4e8eEXTENTORCH\u7814\u7a76<\/strong><\/p>\n\n\n\n

EXTENTORCH\u662f\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u3001\u591a\u4e2d\u5fc3\u7684III\u671f\u7814\u7a76\uff0c\u65e8\u5728\u6bd4\u8f83\u7279\u745e\u666e\u5229\u5355\u6297\u6216\u5b89\u6170\u5242\u8054\u5408\u4f9d\u6258\u6cca\u82f7\u53ca\u94c2\u7c7b\u5728\u4e00\u7ebf\u6cbb\u7597\u5e7f\u6cdb\u671f\u5c0f\u7ec6\u80de\u80ba\u764c\u4e2d\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\u3002\u7531\u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08CSCO\uff09\u526f\u7406\u4e8b\u957f\u3001\u5409\u6797\u7701\u80bf\u7624\u533b\u9662\u7a0b\u9896\u6559\u6388\u62c5\u4efb\u4e3b\u8981\u7814\u7a76\u8005\u3002<\/p>\n\n\n\n

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