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\u5317\u4eac\u65f6\u95f42023\u5e749\u670825\u65e5\uff0c\u541b\u5b9e\u751f\u7269\uff081877.HK\uff0c688180.SH\uff09\u5ba3\u5e03\uff0c\u7531\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\u7684\u6297PD-1\u5355\u6297\u836f\u7269\u7279\u745e\u666e\u5229\u5355\u6297\u5bf9\u6bd4\u8fbe\u5361\u5df4\u55ea\u4e00\u7ebf\u6cbb\u7597\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u7684\u968f\u673a\u3001\u5bf9\u7167\u3001\u591a\u4e2d\u5fc3III\u671f\u4e34\u5e8a\u7814\u7a76\uff08MELATORCH\u7814\u7a76\uff09\u7684\u4e3b\u8981\u7814\u7a76\u7ec8\u70b9\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff0c\u57fa\u4e8e\u72ec\u7acb\u5f71\u50cf\u8bc4\u4f30\uff09\u8fbe\u5230\u65b9\u6848\u9884\u8bbe\u7684\u4f18\u6548\u8fb9\u754c\u3002\u541b\u5b9e\u751f\u7269\u8ba1\u5212\u5c06\u4e8e\u8fd1\u671f\u5411\u76d1\u7ba1\u90e8\u95e8\u9012\u4ea4\u8be5\u65b0\u9002\u5e94\u75c7\u7684\u4e0a\u5e02\u7533\u8bf7\u3002<\/p>\n\n\n\n

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\u4f5c\u4e3a\u56fd\u5185\u9996\u4e2a\u8fbe\u6210\u9633\u6027\u7ed3\u679c\u7684PD-(L)1\u6291\u5236\u5242\u4e00\u7ebf\u6cbb\u7597\u665a\u671f\u9ed1\u8272\u7d20\u7624\u7684\u5173\u952e\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76\uff0cMELATORCH\u7814\u7a76\uff08NCT03430297\uff09\u65e8\u5728\u6bd4\u8f83\u7279\u745e\u666e\u5229\u5355\u6297\u5bf9\u6bd4\u8fbe\u5361\u5df4\u55ea\u5728\u65e2\u5f80\u672a\u63a5\u53d7\u7cfb\u7edf\u6297\u80bf\u7624\u6cbb\u7597\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u4e2d\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\u3002\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u76f8\u8f83\u4e8e\u8fbe\u5361\u5df4\u55ea\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u4e00\u7ebf\u6cbb\u7597\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u53ef\u663e\u8457\u5ef6\u957f\u60a3\u8005\u7684PFS\u3002\u7279\u745e\u666e\u5229\u5355\u6297\u5b89\u5168\u6027\u6570\u636e\u4e0e\u65e2\u5f80\u7814\u7a76\u76f8\u4f3c\uff0c\u672a\u53d1\u73b0\u65b0\u7684\u5b89\u5168\u6027\u4fe1\u53f7\u3002\u672c\u7814\u7a76\u7684\u8be6\u7ec6\u6570\u636e\u5c06\u5728\u540e\u7eed\u7684\u56fd\u9645\u5b66\u672f\u5927\u4f1a\u4e0a\u516c\u5e03\u3002<\/p>\n\n\n\n

MELATORCH\u7814\u7a76\u7684\u7275\u5934\u4e3b\u8981\u7814\u7a76\u8005\u3001\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u90ed\u519b\u6559\u6388<\/strong>\u8868\u793a\uff1a\u201c\u6211\u4eec\u901a\u8fc7\u2161\u671f\u7814\u7a76POLARIS-01\u8bc1\u5b9e\u4e86\u7279\u745e\u666e\u5229\u5355\u6297\u5728\u4e8c\u7ebf\u53ca\u4ee5\u4e0a\u665a\u671f\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u4e2d\u7684\u826f\u597d\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\uff0c\u800c\u672c\u6b21MELATORCH\u7814\u7a76\u7684\u6210\u529f\u5219\u6709\u671b\u8fdb\u4e00\u6b65\u5c06\u7279\u745e\u666e\u5229\u5355\u6297\u6cbb\u7597\u665a\u671f\u9ed1\u8272\u7d20\u7624\u7684\u83b7\u76ca\u4eba\u7fa4\u8303\u56f4\u6269\u5c55\u81f3\u4e00\u7ebf\u60a3\u8005\u3002\u5bf9\u6bd4\u4f20\u7edf\u5316\u7597\u836f\u7269\uff0c\u63a5\u53d7\u7279\u745e\u666e\u5229\u5355\u6297\u5355\u836f\u6cbb\u7597\u7684\u60a3\u8005\u62e5\u6709\u66f4\u4f18\u7684PFS\uff0c\u5e76\u4e14\u5bf9\u4e8e\u4e0d\u540c\u4e9a\u578b\u7684\u60a3\u8005\u5747\u53ef\u5b9e\u73b0\u83b7\u76ca\uff0c\u4e0ePOLARIS-01\u7814\u7a76\u7ed3\u679c\u4e00\u81f4\u3002\u671f\u5f85\u66f4\u591a\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u80fd\u591f\u53d7\u76ca\u4e8e\u6211\u4eec\u7684\u9ad8\u8d28\u91cf\u4e2d\u56fd\u521b\u65b0\u836f\u7269\u3002\u201d<\/p>\n\n\n\n

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\u3010\u53c2\u8003\u6587\u732e\u3011<\/h5>\n\n\n\n
1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021 May;71(3):209-249.<\/h5>\n\n\n\n
2. Wu Y, Wang Y, Wang L, Yin P, Lin Y, Zhou M. Burden of melanoma in China, 1990-2017: Findings from the 2017 global burden of disease study. Int J Cancer. 2020 Aug 1;147(3):692-701.<\/h5>\n\n\n\n
3. \u4e2d\u534e\u4eba\u6c11\u5171\u548c\u56fd\u56fd\u5bb6\u536b\u751f\u5065\u5eb7\u59d4\u5458\u4f1a\u9ed1\u8272\u7d20\u7624\u8bca\u7597\u6307\u5357\uff082022\u5e74\u7248\uff09<\/h5>\n\n\n\n
4. \u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08CSCO\uff09\u9ed1\u8272\u7d20\u7624\u8bca\u7597\u6307\u5357\uff082022\u5e74\u7248\uff09<\/h5>\n\n\n\n

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1. <\/em>\u672c\u6750\u6599\u65e8\u5728\u4f20\u9012\u524d\u6cbf\u4fe1\u606f\uff0c\u65e0\u610f\u5411\u60a8\u505a\u4efb\u4f55\u4ea7\u54c1\u7684\u63a8\u5e7f\uff0c\u4e0d\u4f5c\u4e3a\u4e34\u5e8a\u7528\u836f\u6307\u5bfc\u3002<\/em><\/h6>\n\n\n\n
2. \u82e5\u60a8\u60f3\u4e86\u89e3\u5177\u4f53\u75be\u75c5\u8bca\u7597\u4fe1\u606f\uff0c\u8bf7\u9075\u4ece\u533b\u7597\u536b\u751f\u4e13\u4e1a\u4eba\u58eb\u7684\u610f\u89c1\u4e0e\u6307\u5bfc\u3002<\/em><\/h6>\n\n\n\n
\"\"\/<\/figure>\n\n\n\n

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\u5173\u4e8eMELATORCH\u7814\u7a76<\/strong><\/p>\n\n\n\n

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