{"id":2745,"date":"2024-04-02T18:00:00","date_gmt":"2024-04-02T10:00:00","guid":{"rendered":"https:\/\/dianhuaminglu.com\/?p=2745"},"modified":"2024-04-08T11:49:24","modified_gmt":"2024-04-08T03:49:24","slug":"%e5%90%9b%e5%ae%9e%e7%94%9f%e7%89%a9%e5%ae%a3%e5%b8%83%e6%98%82%e6%88%88%e7%91%9e%e8%a5%bf%e5%8d%95%e6%8a%972%e9%a1%b9%e6%96%b0%e9%80%82%e5%ba%94%e7%97%87%e4%b8%8a%e5%b8%82%e7%94%b3%e8%af%b7%e8%8e%b7","status":"publish","type":"post","link":"https:\/\/dianhuaminglu.com\/%e5%90%9b%e5%ae%9e%e7%94%9f%e7%89%a9%e5%ae%a3%e5%b8%83%e6%98%82%e6%88%88%e7%91%9e%e8%a5%bf%e5%8d%95%e6%8a%972%e9%a1%b9%e6%96%b0%e9%80%82%e5%ba%94%e7%97%87%e4%b8%8a%e5%b8%82%e7%94%b3%e8%af%b7%e8%8e%b7\/","title":{"rendered":"\u541b\u5b9e\u751f\u7269\u5ba3\u5e03\u6602\u6208\u745e\u897f\u5355\u62972\u9879\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u53d7\u7406"},"content":{"rendered":"\n
\u5317\u4eac\u65f6\u95f42024\u5e744\u67082\u65e5\uff0c\u541b\u5b9e\u751f\u7269\uff081877.HK\uff0c688180.SH\uff09\u5ba3\u5e03\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u5df2\u4e8e\u8fd1\u65e5\u53d7\u7406\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\u7684\u6602\u6208\u745e\u897f\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u91cd\u7ec4\u4eba\u6e90\u5316\u6297PCSK9\u5355\u514b\u9686\u6297\u4f53\u6ce8\u5c04\u6db2\uff0c\u4ea7\u54c1\u4ee3\u53f7\uff1aJS002\uff09\u76842\u9879\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\uff0c\u7528\u4e8e\u6cbb\u7597\uff1a1\uff09\u6742\u5408\u5b50\u578b\u5bb6\u65cf\u6027\u9ad8\u80c6\u56fa\u9187\u8840\u75c7\uff1b2\uff09\u4ed6\u6c40\u7c7b\u836f\u7269\u4e0d\u8010\u53d7\u6216\u7981\u5fcc\u4f7f\u7528\u7684\u539f\u53d1\u6027\u9ad8\u80c6\u56fa\u9187\u8840\u75c7\u548c\u6df7\u5408\u578b\u8840\u8102\u5f02\u5e38\u3002\u7533\u62a5\u89c4\u683c\u5206\u522b\u4e3a150mg\uff081ml\uff09\/\u652f\uff08\u9884\u5145\u5f0f\u6ce8\u5c04\u5668\uff09\u3001150mg\uff081ml\uff09\/\u652f\uff08\u9884\u5145\u5f0f\u81ea\u52a8\u6ce8\u5c04\u5668\uff09\u3002<\/p>\n\n\n\n
\u300a\u4e2d\u56fd\u8840\u8102\u7ba1\u7406\u6307\u5357\uff082023\u5e74\uff09\u300b1<\/sup>\u6307\u51fa\uff0c\u5fc3\u8840\u7ba1\u75be\u75c5\u662f\u6211\u56fd\u57ce\u4e61\u5c45\u6c11\u7b2c\u4e00\u4f4d\u6b7b\u56e0\uff0c\u5176\u4e2d\u4ee5\u52a8\u8109\u7ca5\u6837\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u75be\u75c5\uff08ASCVD\uff09\u4e3a\u4e3b\u3002\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u80c6\u56fa\u9187\uff08LDL-C\uff09\u6c34\u5e73\u5347\u9ad8\u662fASCVD\u7684\u81f4\u75c5\u6027\u5371\u9669\u56e0\u7d20\uff0c\u901a\u8fc7\u964d\u4f4eLDL-C\u6c34\u5e73\u53ef\u663e\u8457\u51cf\u5c11ASCVD\u7684\u53d1\u75c5\u53ca\u6b7b\u4ea1\u5371\u9669\u3002\u5c3d\u7ba1\u76ee\u524d\u4ed6\u6c40\u7c7b\u836f\u7269\u5df2\u6210\u4e3a\u964d\u8102\u6cbb\u7597\u7684\u57fa\u7840\uff0c\u4f46\u4e34\u5e8a\u4e0a\u7ea6\u67099.1%\u7684\u60a3\u8005\u5b58\u5728\u4ed6\u6c40\u4e0d\u8010\u53d7\uff0c\u4e14\u5728\u4e9a\u6d32\u4eba\u7fa4\u4e2d\u8be5\u6bd4\u4f8b\u66f4\u9ad82<\/sup>\u3002\u5bf9\u4e8e\u4ed6\u6c40\u4e0d\u8010\u53d7\u60a3\u8005\uff0c\u505c\u7528\u6216\u4ec5\u4f7f\u7528\u53ef\u8010\u53d7\u5242\u91cf\u7684\u4ed6\u6c40\u7c7b\u836f\u7269\u53ef\u80fd\u5bfc\u81f4LDL-C\u6c34\u5e73\u4e0d\u8fbe\u6807\uff0c\u4ece\u800c\u65e0\u6cd5\u8fbe\u5230\u964d\u4f4e\u60a3\u8005ASCVD\u98ce\u9669\u7684\u76ee\u7684\u3002<\/p>\n\n\n\n \u6742\u5408\u5b50\u578b\u5bb6\u65cf\u6027\u9ad8\u80c6\u56fa\u9187\u8840\u75c7\uff08HeFH\uff09\u662f\u5bb6\u65cf\u6027\u9ad8\u80c6\u56fa\u9187\u8840\u75c7\u7684\u5e38\u89c1\u7c7b\u578b\uff0c\u4f30\u6d4b\u60a3\u75c5\u7387 1\/250~1\/200\uff0c\u4e3b\u8981\u4e34\u5e8a\u7279\u5f81\u4e3aLDL-C\u6c34\u5e73\u663e\u8457\u5347\u9ad8\u548c\u65e9\u53d1\u51a0\u5fc3\u75c51<\/sup>\u3002\u4e0e\u975e\u5bb6\u65cf\u6027\u9ad8\u80c6\u56fa\u9187\u8840\u75c7\u60a3\u8005\u76f8\u6bd4\uff0cHeFH\u60a3\u8005\u57fa\u7840LDL-C\u6c34\u5e73\u66f4\u9ad8\u4e14\u6307\u5357\u63a8\u8350\u7684\u63a7\u5236\u76ee\u6807\u6c34\u5e73\u66f4\u4f4e\uff0c\u82e5\u4f7f\u7528\u4ed6\u6c40\u7c7b\u836f\u7269\u7b49\u6cbb\u7597\u540eLDL-C\u672a\u80fd\u8fbe\u6807\uff0c\u5c06\u5bfc\u81f4\u60a3\u8005\u5904\u4e8e\u9ad8\u5fc3\u8840\u7ba1\u98ce\u9669\u3002PCSK9\u6291\u5236\u5242\u4f5c\u4e3a\u5f3a\u6548\u964d\u4f4eLDL-C\u6c34\u5e73\u7684\u65b0\u578b\u964d\u8102\u836f\u7269\uff0c\u5df2\u5f97\u5230\u56fd\u5185\u5916\u8840\u8102\u7ba1\u7406\u6307\u5357\u7684\u63a8\u8350\uff0c\u5e76\u5f97\u5230\u4e34\u5e8a\u533b\u751f\u7684\u5e7f\u6cdb\u8ba4\u53ef\u3002<\/p>\n\n\n\n \u672c\u6b21\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\u4e3b\u8981\u57fa\u4e8e\u4e24\u9879\u6ce8\u518c\u4e34\u5e8a\u8bd5\u9a8c\uff08JS002-005\u3001JS002-007\uff09\u3002\u5176\u4e2d\uff0cJS002-005\uff08NCT05325203\uff09\u662f\u5728\u6742\u5408\u5b50\u578b\u5bb6\u65cf\u6027\u9ad8\u80c6\u56fa\u9187\u8840\u75c7\u6210\u5e74\u60a3\u8005\u4e2d\u5b8c\u6210\u7684\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7684\u2162\u671f\u4e34\u5e8a\u7814\u7a76\uff0cJS002-007\uff08NCT05621070\uff09\u662f\u5728\u4ed6\u6c40\u7c7b\u836f\u7269\u4e0d\u8010\u53d7\u6216\u7981\u5fcc\u4f7f\u7528\u7684\u539f\u53d1\u6027\u9ad8\u80c6\u56fa\u9187\u8840\u75c7\u548c\u6df7\u5408\u578b\u9ad8\u8102\u8840\u75c7\u6210\u5e74\u60a3\u8005\u4e2d\u5b8c\u6210\u7684\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7684\u2162\u671f\u4e34\u5e8a\u7814\u7a76\u3002<\/p>\n\n\n\n <\/p>\n\n\n\n \u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u53d7\u7406\u6602\u6208\u745e\u897f\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u6297PCSK9\u5355\u6297\uff09\u76842\u9879\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7<\/p>\n","protected":false},"author":3,"featured_media":1852,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"yoast_head":"\n\u3010\u53c2\u8003\u6587\u732e\u3011<\/h5>\n\n\n\n
1. \u4e2d\u56fd\u8840\u8102\u7ba1\u7406\u6307\u5357\u4fee\u8ba2\u8054\u5408\u4e13\u5bb6\u59d4\u5458\u4f1a. \u4e2d\u56fd\u8840\u8102\u7ba1\u7406\u6307\u5357\uff082023\u5e74\uff09. \u4e2d\u56fd\u5faa\u73af\u6742\u5fd7. 2023 38;3:237-271.<\/h5>\n\n\n\n
2. Byty\u00e7i I, et al. Prevalence of statin intolerance: a meta-analysis. Eur Heart J. 2022;43(34):3213-3223.<\/h5>\n\n\n\n
1. \u672c\u6750\u6599\u65e8\u5728\u4f20\u9012\u524d\u6cbf\u4fe1\u606f\uff0c\u65e0\u610f\u5411\u60a8\u505a\u4efb\u4f55\u4ea7\u54c1\u7684\u63a8\u5e7f\uff0c\u4e0d\u4f5c\u4e3a\u4e34\u5e8a\u7528\u836f\u6307\u5bfc\u3002<\/em><\/em><\/h6>\n\n\n\n
2. \u82e5\u60a8\u60f3\u4e86\u89e3\u5177\u4f53\u75be\u75c5\u8bca\u7597\u4fe1\u606f\uff0c\u8bf7\u9075\u4ece\u533b\u7597\u536b\u751f\u4e13\u4e1a\u4eba\u58eb\u7684\u610f\u89c1\u4e0e\u6307\u5bfc\u3002<\/em><\/em><\/h6>\n","protected":false},"excerpt":{"rendered":"