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class=\"wp-block-heading\"><em>1. <\/em><em>\u672c\u6750\u6599\u65e8\u5728\u50b3\u905e\u524d\u6cbf\u8cc7\u8a0a\uff0c\u7121\u610f\u5411\u60a8\u505a\u4efb\u4f55\u7522\u54c1\u7684\u63a8\u5ee3\uff0c\u4e0d\u4f5c\u70ba\u81e8\u5e8a\u7528\u85e5\u6307\u5c0e\u3002<\/em><em><\/em><\/h6>\n\n\n\n<h6 class=\"wp-block-heading\"><em>2. \u82e5\u60a8\u60f3\u77ad\u89e3\u5177\u9ad4\u75be\u75c5\u8a3a\u7642\u8cc7\u8a0a\uff0c\u8acb\u9075\u5f9e\u91ab\u7642\u885b\u751f\u5c08\u696d\u4eba\u58eb\u7684\u610f\u898b\u8207\u6307\u5c0e\u3002<\/em><\/h6>\n\n\n\n\n\n<p><strong>\u95dc\u65bc\u6c11\u5f97\u7dad<\/strong><strong><sup>\u00ae<\/sup><\/strong><strong>\uff08\u6c2b\u6eb4\u9178\u6c18\u745e\u7c73\u5fb7\u97cb\u7247\uff0c<\/strong><strong>VV116\/JT001<\/strong><strong>\uff09<\/strong><strong><\/strong><\/p>\n\n\n\n<p>VV116\u662f\u4e00\u6b3e\u53e3\u670d\u6838\u82f7\u985e\u85e5\u7269\uff0c\u53ef\u6291\u5236SARS-CoV-2\u8907\u88fd\u3002\u81e8\u5e8a\u524d\u85e5\u6548\u5b78\u7814\u7a76\u986f\u793a\uff0cVV116\u5728\u9ad4\u5916\u5c0d\u5305\u62ec\u5967\u5bc6\u514b\u620e\u5728\u5167\u7684\u65b0\u51a0\u75c5\u6bd2\u539f\u59cb\u682a\u548c\u7a81\u8b8a\u682a\u8868\u73fe\u51fa\u986f\u8457\u7684\u6297\u75c5\u6bd2\u4f5c\u7528\uff1b\u5728\u5c0f\u9f20\u6a21\u578b\u4e0a\uff0c\u4f4e\u5291\u91cf\u7684VV116\u5c31\u53ef\u5c07\u80ba\u90e8\u75c5\u6bd2\u6ef4\u5ea6\u964d\u4f4e\u81f3\u6aa2\u6e2c\u9650\u4ee5\u4e0b\uff0c\u53ef\u986f\u8457\u6539\u5584\u80ba\u7d44\u7e54\u75c5\u7406\u8b8a\u5316\uff0c\u8868\u73fe\u51fa\u8f03\u5f37\u7684\u6297\u75c5\u6bd2\u529f\u6548\u3002\u81e8\u5e8a\u524d\u7684\u85e5\u4ee3\u52d5\u529b\u5b78\u7b49\u7814\u7a76\u7d50\u679c\u986f\u793a\uff0cVV116\u5177\u6709\u5f88\u9ad8\u7684\u53e3\u670d\u751f\u7269\u5229\u7528\u5ea6\uff0c\u5176\u53e3\u670d\u5438\u6536\u5f8c\uff0c\u8fc5\u901f\u4ee3\u8b1d\u70ba\u6bcd\u9ad4\u6838\u82f7\uff0c\u4e26\u5728\u9ad4\u5167\u7d44\u7e54\u5ee3\u6cdb\u5206\u4f48\u3002<\/p>\n\n\n\n<p>VV116\u7531\u4e2d\u570b\u79d1\u5b78\u9662\u4e0a\u6d77\u85e5\u7269\u7814\u7a76\u6240\u3001\u4e2d\u570b\u79d1\u5b78\u9662\u6b66\u6f22\u75c5\u6bd2\u7814\u7a76\u6240\u3001\u4e2d\u570b\u79d1\u5b78\u9662\u65b0\u7586\u7406\u5316\u6280\u8853\u7814\u7a76\u6240\u3001\u4e2d\u570b\u79d1\u5b78\u9662\u4e2d\u4e9e\u85e5\u7269\u7814\u767c\u4e2d\u5fc3\/\u4e2d\u70cf\u91ab\u85e5\u79d1\u6280\u57ce\uff08\u79d1\u6280\u90e8\u201c\u4e00\u5e36\u4e00\u8def\u201d\u806f\u5408\u5be6\u9a57\u5ba4\uff09\u3001\u81e8\u6e2f\u5be6\u9a57\u5ba4\u3001\u8607\u5dde\u65fa\u5c71\u65fa\u6c34\u751f\u7269\u91ab\u85e5\u6709\u9650\u516c\u53f8\uff08\u65fa\u5c71\u65fa\u6c34\uff09\u548c\u541b\u5be6\u751f\u7269\u5171\u540c\u7814\u767c\u3002\u541b\u5be6\u751f\u7269\u8207\u65fa\u5c71\u65fa\u6c34\u5171\u540c\u627f\u64d4\u8a72\u85e5\u7269\u5728\u5168\u7403\u5c64\u9762\u7684\u81e8\u5e8a\u958b\u767c\u548c\u7522\u696d\u5316\u5de5\u4f5c\uff0c\u5408\u4f5c\u5340\u57df\u70ba\u9664\u4e2d\u4e9e\u4e94\u570b\u3001\u4fc4\u7f85\u65af\u3001\u5317\u975e\u3001\u4e2d\u6771\u56db\u500b\u5340\u57df\u5916\u7684\u5168\u7403\u7bc4\u570d\u3002<\/p>\n\n\n\n<p>\u541b\u5be6\u751f\u7269\u8207\u65fa\u5c71\u65fa\u6c34\u5df2\u5728\u4e2d\u570b\u5065\u5eb7\u53d7\u8a66\u8005\u4e2d\u5b8c\u6210\u4e863\u9805I\u671f\u81e8\u5e8a\u7814\u7a76<sup>[1]<\/sup>\uff0c\u4e26\u5728\u4e2d\u570b\u4f34\u6709\u9032\u5c55\u70ba\u91cd\u75c7\u9ad8\u98a8\u96aa\u56e0\u7d20\u7684\u8f15\u4e2d\u5ea6COVID-19\u60a3\u8005\u4e2d\u5b8c\u62101\u9805III\u671f\u81e8\u5e8a\u7814\u7a76<sup>[2]<\/sup>\uff08NCT05341609\uff09\uff0c\u7814\u7a76\u7d50\u679c\u5206\u5225\u767c\u8868\u65bc<em>Acta Pharmacologica Sinica<\/em>\u548c\u300a\u65b0\u82f1\u683c\u862d\u91ab\u5b78\u96dc\u8a8c\u300b\uff08<em>The New England Journal of Medicine<\/em>\uff09\u3002\u53e6\uff0c1\u9805\u5728\u4f34\u6216\u4e0d\u4f34\u6709\u9032\u5c55\u91cd\u75c7\u9ad8\u98a8\u96aa\u56e0\u7d20\u7684\u8f15\u4e2d\u5ea6COVID-19\u60a3\u8005\u4e2d\u958b\u5c55\u7684III\u671f\u7814\u7a76\u5df2\u5b8c\u6210\u65b9\u6848\u9810\u8a2d\u7684\u671f\u4e2d\u5206\u6790\uff0c\u9054\u6210\u65b9\u6848\u9810\u8a2d\u898f\u5b9a\u7684\u4e3b\u8981\u6709\u6548\u6027\u7d42\u9ede\u3002<\/p>\n\n\n\n<p>2021\u5e7412\u6708\uff0cVV116\u5728\u70cf\u8332\u5225\u514b\u65af\u5766\u7372\u5f97\u6279\u51c6\u7528\u65bc\u6cbb\u7642\u4e2d\/\u91cd\u5ea6COVID-19\u60a3\u8005\u3002<\/p>\n\n\n\n<p>2023\u5e741\u6708\uff0cVV116\u5728\u4e2d\u570b\u7372\u5f97\u6279\u51c6\u7528\u65bc\u6cbb\u7642\u8f15\u4e2d\u5ea6COVID-19\u7684\u6210\u5e74\u60a3\u8005\u3002<\/p>\n\n\n\n<h5 class=\"wp-block-heading\">\u3010\u53c3\u8003\u6587\u737b\u3011<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">[1] Qian, Hj., et al. Acta Pharmacol Sin (2022).<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">[2] Cao Z, Gao W, Bao H, et al. VV116 versus Nirmatrelvir\u2013Ritonavir for Oral Treatment of Covid-19. N Engl J Med. DOI: 10.1056\/NEJMoa2208822.<\/h5>\n\n\n","protected":false},"excerpt":{"rendered":"<p>\u5317\u4eac\u6642\u95932023\u5e741\u670829\u65e5\uff0c\u541b\u5be6\u751f\u7269\uff081877.HK\uff0c688180.SH\uff09\u5ba3\u4f48\uff0c\u516c\u53f8\u65d7\u4e0b\u7684\u53e3\u670d\u6838\u82f7\u985e\u6297\u65b0\u578b\u51a0\u72c0\u75c5\u6bd2\uff08SARS-CoV-2\uff09\u85e5\u7269\u6c11\u5f97\u7dad\u00ae\uff08\u6c2b\u6eb4\u9178\u6c18\u745e\u7c73\u5fb7\u97cb\u7247\uff0c\u7522\u54c1\u4ee3\u865f\uff1aVV116\/JT001\uff09\u7372\u5f97\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\uff0c\u7528\u65bc\u6cbb\u7642\u8f15\u4e2d\u5ea6\u65b0\u578b\u51a0\u72c0\u75c5\u6bd2\u611f\u67d3\uff08COVID-19\uff09\u7684\u6210\u5e74\u60a3\u8005\u3002<\/p>\n","protected":false},"author":3,"featured_media":1286,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[21],"tags":[],"class_list":["post-1766","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-21"],"yoast_head":"\n<title>\u541b\u5be6\u751f\u7269\u5ba3\u4f48\u53e3\u670d\u6297\u65b0\u51a0\u75c5\u6bd2\u85e5\u7269\u6c11\u5f97\u7dad\u00ae\uff08VV116\uff09\u7372\u5f97\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\u6279\u51c6 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