{"id":2156,"date":"2023-04-21T10:53:22","date_gmt":"2023-04-21T10:53:22","guid":{"rendered":"https:\/\/dianhuaminglu.com\/%e5%90%9b%e5%ae%9e%e7%94%9f%e7%89%a9%e9%a6%96%e6%ac%a1%e5%85%ac%e5%b8%83%e7%89%b9%e7%91%9e%e6%99%ae%e5%88%a9%e5%8d%95%e6%8a%97%e5%9b%b4%e6%89%8b%e6%9c%af%e6%9c%9f%e6%b2%bb%e7%96%97%e9%9d%9e%e5%b0%8f\/"},"modified":"2023-05-04T10:38:29","modified_gmt":"2023-05-04T10:38:29","slug":"%e5%90%9b%e5%ae%9e%e7%94%9f%e7%89%a9%e9%a6%96%e6%ac%a1%e5%85%ac%e5%b8%83%e7%89%b9%e7%91%9e%e6%99%ae%e5%88%a9%e5%8d%95%e6%8a%97%e5%9b%b4%e6%89%8b%e6%9c%af%e6%9c%9f%e6%b2%bb%e7%96%97%e9%9d%9e%e5%b0%8f","status":"publish","type":"post","link":"https:\/\/dianhuaminglu.com\/zh-hant\/%e5%90%9b%e5%ae%9e%e7%94%9f%e7%89%a9%e9%a6%96%e6%ac%a1%e5%85%ac%e5%b8%83%e7%89%b9%e7%91%9e%e6%99%ae%e5%88%a9%e5%8d%95%e6%8a%97%e5%9b%b4%e6%89%8b%e6%9c%af%e6%9c%9f%e6%b2%bb%e7%96%97%e9%9d%9e%e5%b0%8f\/","title":{"rendered":"\u541b\u5be6\u751f\u7269\u9996\u6b21\u516c\u4f48\u7279\u745e\u666e\u5229\u55ae\u6297\u570d\u624b\u8853\u671f\u6cbb\u7642\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u7684\u4e09\u671f\u7814\u7a76\u8cc7\u6599\uff0c\u75be\u75c5\u5fa9\u767c\u3001\u9032\u5c55\u6216\u6b7b\u4ea1\u98a8\u96aa\u964d\u4f4e\u905460%"},"content":{"rendered":"\n<ul class=\"wp-block-list\">\n<li><em>Neotorch<\/em><em>\u7814\u7a76\u662f\u5168\u7403\u9996\u500b\u6297<\/em><em>PD-1<\/em><em>\u55ae\u6297\u7528\u65bc\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u570d\u624b\u8853\u671f\u6cbb\u7642\u9054\u5230\u4e3b\u8981\u7d42\u9ede\u7684<\/em><em>III<\/em><em>\u671f\u81e8\u5e8a\u7814\u7a76\uff0c\u7279\u745e\u666e\u5229\u55ae\u6297\u986f\u8457\u5ef6\u9577\u4e86\u7121\u4e8b\u4ef6\u751f\u5b58\u671f\uff08<\/em><em>EFS<\/em><em>\uff09\uff0c\u75be\u75c5\u5fa9\u767c\u3001\u9032\u5c55\u6216\u6b7b\u4ea1\u98a8\u96aa\u964d\u4f4e\u9054<\/em><em>60%<\/em><em><\/em><\/li>\n\n\n\n<li><em>\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u7d44\u7684\u4e3b\u8981\u75c5\u7406\u7de9\u89e3\uff08<\/em><em>MPR<\/em><em>\uff09\u7387\u548c\u5b8c\u5168\u75c5\u7406\u7de9\u89e3\uff08<\/em><em>pCR<\/em><em>\uff09\u7387\u65b9\u9762\u5747\u512a\u65bc\u55ae\u7d14\u5316\u7642\u7d44\uff0c\u5206\u5225\u70ba<\/em><em>48.5% vs 8.4%<\/em><em>\u548c<\/em><em>24.8% vs 1.0%<\/em><\/li>\n\n\n\n<li><em>\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u7d44\u7684\u7e3d\u751f\u5b58\u671f\uff08OS\uff09\u986f\u793a\u51fa\u660e\u986f\u7684\u7372\u76ca\u8da8\u52e2<\/em><\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<p>\u5317\u4eac\u6642\u95932023\u5e744\u670821\u65e5\uff0c\u541b\u5be6\u751f\u7269\uff081877.HK\uff0c688180.SH\uff09\u5ba3\u4f48\uff0c\u7531\u516c\u53f8\u81ea\u4e3b\u7814\u767c\u7684\u6297PD-1\u55ae\u6297\u85e5\u7269\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u7528\u65bc\u53ef\u624b\u8853\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u570d\u624b\u8853\u671f\u6cbb\u7642III\u671f\u81e8\u5e8a\u7814\u7a76\uff08Neotorch\uff09\u6210\u679c\u4ee5\u53e3\u982d\u5831\u544a\u5f62\u5f0f\u5728\u7f8e\u570b\u81e8\u5e8a\u816b\u7624\u5b78\u6703\u5168\u9ad4\u5927\u6703\u7cfb\u5217\uff08ASCO Plenary Series\uff094\u6708\u6703\u8b70\u4e0a\u9032\u884c\u4e86\u5168\u7403\u9996\u767c\u516c\u4f48\u3002\u7814\u7a76\u8b49\u5be6\uff0c\u76f8\u8f03\u55ae\u7d14\u5316\u7642\uff0c\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u7528\u65bc\u53ef\u624b\u8853III\u671fNSCLC\u570d\u624b\u8853\u671f\u6cbb\u7642\u53ef\u986f\u8457\u5ef6\u9577\u60a3\u8005\u7684\u7121\u4e8b\u4ef6\u751f\u5b58\u671f\uff08EFS\uff09\uff0c\u63d0\u5347\u4e3b\u8981\u75c5\u7406\u7de9\u89e3\uff08MPR\uff09\u7387\u548c\u5b8c\u5168\u75c5\u7406\u7de9\u89e3\uff08pCR\uff09\u7387\uff0c\u4e26\u4e14\u66f4\u591a\u60a3\u8005\u53ef\u901a\u904e\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u6cbb\u7642\u7372\u5f97\u6839\u6cbb\u6027\u624b\u8853\u7684\u6a5f\u6703\u3002<\/p>\n\n\n\n<p>ASCO Plenary Series\u6bcf\u6708\u8209\u8fa6\u4e00\u6b21\uff0c\u901a\u904eASCO\u5c08\u5bb6\u59d4\u54e1\u6703\u6311\u9078\u81f3\u591a2\u7bc7\u975e\u5e38\u5177\u6709\u4ee3\u8868\u6027\u7684\u91cd\u78c5\u7814\u7a76\u8cc7\u6599\u9032\u884c\u516c\u4f48\u548c\u8a0e\u8ad6\uff0c\u65e8\u5728\u53ca\u6642\u66f4\u65b0\u5177\u6709\u5275\u65b0\u6027\u3001\u9ad8\u54c1\u8cea\u4ee5\u53ca\u91cd\u8981\u81e8\u5e8a\u5be6\u8e10\u610f\u7fa9\u7684\u81e8\u5e8a\u7814\u7a76\u8cc7\u6599\uff0c\u4fc3\u9032\u5168\u7403\u816b\u7624\u6cbb\u7642\u65b9\u6848\u66f4\u65b0\uff0c\u60e0\u53ca\u60a3\u8005\u3002<\/p>\n\n\n\n<p>Neotorch\u7814\u7a76\uff08NCT04158440\uff09\u662f\u4e00\u9805\u96a8\u6a5f\u3001\u96d9\u76f2\u3001\u5b89\u6170\u5291\u5c0d\u7167\u7684III\u671f\u81e8\u5e8a\u7814\u7a76\uff0c\u65e8\u5728\u6bd4\u8f03\u7279\u745e\u666e\u5229\u55ae\u6297\u6216\u5b89\u6170\u5291\u806f\u5408\u5316\u7642\u7528\u65bcII\/III\u671f\u53ef\u624b\u8853NSCLC\u60a3\u8005\u570d\u624b\u8853\u671f\u6cbb\u7642\u7684\u7642\u6548\u548c\u5b89\u5168\u6027\uff0c\u7531\u4e0a\u6d77\u4ea4\u901a\u5927\u5b78\u9644\u5c6c\u80f8\u79d1\u91ab\u9662\u9678\u821c\u6559\u6388\u727d\u982d\u958b\u5c55\u30022023\u5e741\u6708\uff0cNeotorch\u7814\u7a76\u5b8c\u6210\u65b9\u6848\u9810\u8a2d\u7684\u671f\u4e2d\u5206\u6790\uff0c\u6210\u70ba\u5168\u7403\u9996\u500b\u6297PD-1\u55ae\u6297\u7528\u65bcNSCLC\u570d\u624b\u8853\u671f\uff08\u6db5\u84cb\u65b0\u8f14\u52a9\u548c\u8f14\u52a9\u6cbb\u7642\uff09\u6cbb\u7642\u9054\u5230EFS\u967d\u6027\u7d50\u679c\u7684III\u671f\u81e8\u5e8a\u7814\u7a76\u3002<\/p>\n\n\n\n<p>Neotorch\u7814\u7a76\u5171\u7d0d\u5165404\u4f8bIII\u671fNSCLC\u60a3\u8005\uff0c\u4ee51:1\u7684\u6bd4\u4f8b\u88ab\u96a8\u6a5f\u5206\u914d\u81f3\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u7d44\uff08n=202\uff09\u6216\u5b89\u6170\u5291\u806f\u5408\u5316\u7642\u7d44\uff08n=202\uff09\uff0c\u5206\u5225\u63a5\u53d7\u7279\u745e\u666e\u5229\u55ae\u6297\u6216\u5b89\u6170\u5291\u806f\u5408\u5316\u7642\u8853\u524d3\u9031\u671f\u53ca\u8853\u5f8c1\u9031\u671f\u6cbb\u7642\uff08\u9c57\u764c\u60a3\u8005\u5316\u7642\u65b9\u6848\u70ba\u7d2b\u6749\u985e+\u9251\u985e\uff0c\u975e\u9c57\u764c\u60a3\u8005\u5316\u7642\u65b9\u6848\u70ba\u57f9\u7f8e\u66f2\u585e+\u9251\u985e\uff09\uff0c\u96a8\u5f8c\u63a5\u53d7\u7279\u745e\u666e\u5229\u55ae\u6297\u6216\u5b89\u6170\u5291\u978f\u56fa\u6cbb\u764213\u9031\u671f\u3002<\/p>\n\n\n\n<p>\u622a\u81f32022\u5e7411\u670830\u65e5\uff08\u4e2d\u4f4d\u96a8\u8a2a\u6642\u959318.25\u500b\u6708\uff09\uff0c\u7d50\u679c\u986f\u793a\uff1a\u8207\u55ae\u7d14\u5316\u7642\u76f8\u6bd4\uff0c\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u7528\u65bcIII\u671f\u53ef\u624b\u8853NSCLC\u60a3\u8005\u570d\u624b\u8853\u671f\u6cbb\u7642\u4e26\u5728\u5f8c\u7e8c\u9032\u884c\u7279\u745e\u666e\u5229\u55ae\u6297\u55ae\u85e5\u978f\u56fa\u6cbb\u7642\uff0c\u53ef\u986f\u8457\u5ef6\u9577\u60a3\u8005EFS\uff08\u7814\u7a76\u8005\u8a55\u4f30\u7684\u4e2d\u4f4dEFS\u5206\u5225\u70ba\u5c1a\u672a\u6210\u719f vs 15.1\u500b\u6708\uff0cP&lt;0.0001\uff09\uff0c\u75be\u75c5\u5fa9\u767c\u3001\u9032\u5c55\u6216\u6b7b\u4ea1\u98a8\u96aa\u964d\u4f4e\u905460%\uff08HR=0.40\uff0c95%CI\uff1a0.277-0.565\uff0c\u96d9\u5074P&lt;0.0001\uff09\u3002\u5169\u7d44\u76841\u5e74EFS\u7387\u548c2\u5e74EFS\u7387\u5206\u5225\u70ba84.4% vs 57.0%\u548c64.7% vs 38.7%\u3002<\/p>\n\n\n\n<p>\u540c\u6642\uff0c\u7d93\u76f2\u614b\u7368\u7acb\u4e2d\u5fc3\u75c5\u7406\uff08BIPR\uff09\u8a55\u4f30\uff0c\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u7d44\u7684\u4e3b\u8981\u75c5\u7406\u7de9\u89e3\uff08MPR\uff09\u7387\u548c\u5b8c\u5168\u75c5\u7406\u7de9\u89e3\uff08pCR\uff09\u7387\u65b9\u9762\u5747\u512a\u65bc\u55ae\u7d14\u5316\u7642\u7d44\uff0c\u5206\u5225\u70ba48.5% vs 8.4%\uff08P\uff1c0.0001\uff09\u548c24.8% vs 1.0%\uff08P\uff1c0.0001\uff09\u3002\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u7d44\u7684\u7e3d\u751f\u5b58\u671f\uff08OS\uff09\u4e5f\u986f\u793a\u51fa\u660e\u986f\u7684\u7372\u76ca\u8da8\u52e2\u3002\u5169\u7d44\u4e2d\u4f4dOS\u5206\u5225\u70ba\u672a\u6210\u719f vs 30.4\u500b\u6708\uff08HR=0.62\uff0c95% CI: 0.381-0.999\uff09\uff1b1\u5e74OS\u7387\u548c2\u5e74OS\u7387\u5206\u5225\u70ba94.4% vs 89.6%\u548c81.2% vs 74.3%\u3002\u60a3\u8005\u5c07\u7e7c\u7e8c\u9032\u884cOS\u96a8\u8a2a\u3002<\/p>\n\n\n\n<p>\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u65b0\u8f14\u52a9\u6cbb\u7642\u5f8c\uff0c\u76f8\u6bd4\u5b89\u6170\u5291\u806f\u5408\u5316\u7642\u7d44\uff0c\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u7d44\u4e2d\u6709\u66f4\u9ad8\u6bd4\u4f8b\u7684\u60a3\u8005\u63a5\u53d7\u4e86\u6839\u6cbb\u76ee\u7684\u7684\u624b\u8853\uff0882.2% vs 73.3%\uff09\uff0c\u63d0\u793a\u5728\u5316\u7642\u57fa\u790e\u4e0a\u806f\u5408\u7279\u745e\u666e\u5229\u55ae\u6297\u6cbb\u7642\u70ba\u66f4\u591a\u60a3\u8005\u5e36\u4f86\u4e86\u6839\u6cbb\u6027\u6cbb\u7642\u7684\u6a5f\u6703\u3002<\/p>\n\n\n\n<p>\u5b89\u5168\u6027\u65b9\u9762\uff0c\u5169\u7d44\u6cbb\u7642\u671f\u9593\u51fa\u73fe\u7684\u4e0d\u826f\u4e8b\u4ef6\uff08TEAE\uff09\u767c\u751f\u7387\u76f8\u4f3c\uff0c\u672a\u89c0\u5bdf\u5230\u65b0\u7684\u5b89\u5168\u6027\u4fe1\u865f\u3002<\/p>\n\n\n\n<p>2023\u5e744\u6708\uff0c\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u5df2\u53d7\u7406\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u570d\u624b\u8853\u671f\u6cbb\u7642\u4e26\u672c\u54c1\u55ae\u85e5\u4f5c\u70ba\u8f14\u52a9\u6cbb\u7642\u5f8c\u978f\u56fa\u6cbb\u7642\uff0c\u7528\u65bc\u53ef\u5207\u9664III\u671f\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u7684\u6cbb\u7642\u7684\u65b0\u9069\u61c9\u75c7\u4e0a\u5e02\u7533\u8acb\u3002<\/p>\n\n\n\n<p><strong>Neotorch<\/strong><strong>\u4e3b\u8981\u7814\u7a76\u8005\u3001\u4e0a\u6d77\u4ea4\u901a\u5927\u5b78\u9644\u5c6c\u80f8\u79d1\u91ab\u9662\u9678\u821c\u6559\u6388<\/strong>\u8868\u793a\uff1a\u201cNeotorch\u7814\u7a76\u958b\u5275\u4e86\u5168\u7403\u9996\u500b\u20183+1+13\u2019NSCLC\u570d\u624b\u8853\u671f\u6cbb\u7642\u6a21\u5f0f\uff0c\u5c07\u514d\u75ab\u6cbb\u7642\u8cab\u7a7f\u8853\u524d\u65b0\u8f14\u52a9\u548c\u8853\u5f8c\u8f14\u52a9\u6cbb\u7642\u3002\u7d50\u679c\u986f\u793a\uff0c\u5728\u5316\u7642\u57fa\u790e\u4e0a\u806f\u7528\u7279\u745e\u666e\u5229\u55ae\u6297\u80fd\u5920\u986f\u8457\u5ef6\u9577NSCLC\u60a3\u8005\u7684EFS\uff0c2\u5e74EFS\u7387\u9060\u8d85\u55ae\u7d14\u5316\u7642\uff0c\u8cc7\u6599\u8868\u73fe\u512a\u65bc\u5df2\u5831\u5c0e\u7684\u5176\u5b83\u985e\u4f3cIII\u671f\u7814\u7a76\uff0c\u4e0d\u50c5\u5f70\u986f\u4e86\u4e2d\u570b\u539f\u5275\u7814\u7a76\u7684\u5f37\u5927\u5be6\u529b\uff0c\u4e5f\u898b\u8b49\u4e86\u4e2d\u570b\u539f\u5275\u7814\u7a76\u5f9e\u8ddf\u8dd1\u5230\u9818\u8dd1\u7684\u5de8\u5927\u8f49\u8b8a\u3002\u4f5c\u70ba\u8fc4\u4eca\u70ba\u6b62\u4e2d\u570b\u6700\u5927\u6a23\u672c\u7684NSCLC\u570d\u624b\u8853\u671f\u524d\u77bb\u6027III\u671f\u81e8\u5e8a\u7814\u7a76\uff0cNeotorch\u66f4\u8cbc\u8fd1\u4e2d\u570b\u81e8\u5e8a\u5be6\u8e10\uff0c\u975e\u5e38\u671f\u5f85\u9019\u9805\u9996\u5275\u65b9\u6848\u80fd\u5920\u9032\u4e00\u6b65\u63d0\u5347\u6211\u570b\u80ba\u764c\u514d\u75ab\u6cbb\u7642\u85e5\u7269\u7684\u53ef\u53ca\u6027\uff0c\u70ba\u60a3\u8005\u9ede\u71c3\u751f\u547d\u65b0\u5e0c\u671b\uff01\u201d<\/p>\n\n\n\n<p><strong>\u5927\u6703\u9ede\u8a55\u5c08\u5bb6\u3001\u8cd3\u5915\u6cd5\u5c3c\u4e9e\u5927\u5b78\u4f69\u96f7\u723e\u66fc\u91ab\u5b78\u9662Charu Aggarwal\u6559\u6388<\/strong>\u8868\u793a\uff1a\u201cNeotorch\u7814\u7a76\u5efa\u7acb\u5728\u53ef\u624b\u8853NSCLC\u60a3\u8005\u7576\u524d\u7684\u6a19\u6e96\u7642\u6cd5\u2014\u2014\u8853\u524d\u514d\u75ab\u806f\u5408\u5316\u7642\u65b0\u8f14\u52a9\u6cbb\u7642\u4e4b\u4e0a\uff0c\u8b49\u660e\u4e86\u4e00\u7a2e\u570d\u624b\u8853\u671f\u514d\u75ab\u6cbb\u7642\u6f5b\u5728\u65b0\u6a21\u5f0f\u3002\u201d<\/p>\n\n\n\n<p><strong>\u541b\u5be6\u751f\u7269\u5168\u7403\u7814\u767c\u7e3d\u88c1\u9112\u5efa\u8ecd\u535a\u58eb<\/strong>\u8868\u793a\uff1a\u201c\u80ba\u764c\u662f\u5168\u7403\u6b7b\u4ea1\u7387\u6700\u9ad8\u7684\u60e1\u6027\u816b\u7624\uff0c\u5373\u4fbf\u65e9\u671f\u901a\u904e\u6839\u6cbb\u6027\u624b\u8853\u5207\u9664\u816b\u7624\uff0c\u4ecd\u6709\u4e00\u5b9a\u6bd4\u4f8b\u7684\u60a3\u8005\u5728\u8853\u5f8c\u767c\u751f\u5fa9\u767c\u751a\u81f3\u6b7b\u4ea1\u3002\u5982\u4eca\uff0c\u514d\u75ab\u6cbb\u7642\u5df2\u5728\u591a\u7a2e\u665a\u671f\u816b\u7624\u6cbb\u7642\u4e2d\u78ba\u7acb\u4e86\u6a19\u6e96\u6cbb\u7642\u5730\u4f4d\uff0c\u800c\u91dd\u5c0d\u75c5\u7a0b\u65e9\u671f\u7684\u61c9\u7528\u63a2\u7d22\u4e5f\u6f38\u5165\u4f73\u5883\u3002\u541b\u5be6\u751f\u7269\u662f\u672c\u571f\u85e5\u4f01\u4e2d\u5728\u816b\u7624\u8853\u5f8c\u8f14\u52a9\/\u570d\u624b\u8853\u671f\u6cbb\u7642\u9818\u57df\u6700\u5148\u958b\u5c55\u81e8\u5e8a\u8a66\u9a57\u3001\u8986\u84cb\u9069\u61c9\u75c7\u6700\u5ee3\u7684\u4f01\u696d\u4e4b\u4e00\uff0c\u6b64\u6b21Neotorch\u7814\u7a76\u7684\u9a5a\u8c54\u6210\u679c\u66f4\u5805\u5b9a\u4e86\u6211\u5011\u70ba\u816b\u7624\u60a3\u8005\u5c0b\u6c42\u6cbb\u7652\u5e0c\u671b\u7684\u6c7a\u5fc3\u3002\u76ee\u524d\u57fa\u65bcNeotorch\u8cc7\u6599\u7684\u65b0\u9069\u61c9\u75c7\u4e0a\u5e02\u7533\u8acb\u6b63\u5728\u63a5\u53d7\u4e2d\u570b\u85e5\u76e3\u6a5f\u69cb\u5be9\u8a55\uff0c\u671f\u5f85\u5728\u5404\u65b9\u7684\u5171\u540c\u52aa\u529b\u4e0b\u63a8\u52d5\u9019\u9805\u5275\u65b0\u7642\u6cd5\u53ca\u65e9\u60e0\u53ca\u672c\u571f\u80ba\u764c\u60a3\u8005\uff01\u201d<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h5 class=\"wp-block-heading\">\u3010\u53c3\u8003\u6587\u737b\u3011<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">1.ASCO\u5b98\u7db2<\/h5>\n\n\n\n<p><\/p>\n\n\n\n<h6 class=\"wp-block-heading\"><em>1. \u672c\u6750\u6599\u65e8\u5728\u50b3\u905e\u524d\u6cbf\u8cc7\u8a0a\uff0c\u7121\u610f\u5411\u60a8\u505a\u4efb\u4f55\u7522\u54c1\u7684\u63a8\u5ee3\uff0c\u4e0d\u4f5c\u70ba\u81e8\u5e8a\u7528\u85e5\u6307\u5c0e\u3002<\/em><\/h6>\n\n\n\n<h6 class=\"wp-block-heading\"><em>2.&nbsp;\u82e5\u60a8\u60f3\u77ad\u89e3\u5177\u9ad4\u75be\u75c5\u8a3a\u7642\u8cc7\u8a0a\uff0c\u8acb\u9075\u5f9e\u91ab\u7642\u885b\u751f\u5c08\u696d\u4eba\u58eb\u7684\u610f\u898b\u8207\u6307\u5c0e\u3002<\/em><\/h6>\n\n\n\n\n\n<p><strong>\u95dc\u65bc\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08<\/strong><strong>NSCLC<\/strong><strong>\uff09<\/strong><strong><\/strong><\/p>\n\n\n\n<p>\u80ba\u764c\u662f\u76ee\u524d\u5168\u7403\u767c\u75c5\u7387\u7b2c\u4e8c\u3001\u6b7b\u4ea1\u7387\u7b2c\u4e00\u7684\u60e1\u6027\u816b\u7624<sup>1<\/sup>\u3002\u64da\u7d71\u8a08\uff0c2020\u5e74\u4e2d\u570b\u7684\u80ba\u764c\u75c5\u4f8b\u6578\u5360\u65b0\u767c\u764c\u75c7\u75c5\u4f8b\u6578\u768417.9%\uff0881.6\u842c\uff09\uff0c\u764c\u75c7\u6b7b\u4ea1\u75c5\u4f8b\u6578\u768423.8%\uff0871.5\u842c\uff09<sup>2<\/sup>\u3002NSCLC\u70ba\u80ba\u764c\u7684\u4e3b\u8981\u4e9e\u578b\uff0c\u7d04\u5360\u6240\u6709\u75c5\u4f8b\u768485%<sup>3<\/sup>\u3002\u5176\u4e2d\uff0c20-25%\u7684\u60a3\u8005\u521d\u8a3a\u53ef\u624b\u8853\u5207\u9664<sup>4<\/sup>\uff0c\u4f46\u5373\u4fbf\u63a5\u53d7\u4e86\u6839\u6cbb\u6027\u624b\u8853\u6cbb\u7642\uff0c\u4ecd\u670930-55%\u7684\u60a3\u8005\u6703\u5728\u8853\u5f8c\u767c\u751f\u5fa9\u767c\u4e26\u6b7b\u4ea1<sup>5,6<\/sup>\u3002\u6839\u6cbb\u6027\u624b\u8853\u806f\u5408\u5316\u7642\u662f\u9810\u9632\u75be\u75c5\u5fa9\u767c\u7684\u624b\u6bb5\u4e4b\u4e00\uff0c\u4f46\u5316\u7642\u4f5c\u70ba\u8853\u524d\u65b0\u8f14\u52a9\u6216\u8853\u5f8c\u8f14\u52a9\u6cbb\u7642\u7684\u81e8\u5e8a\u7372\u76ca\u6709\u9650\uff0c\u50c5\u80fd\u5c07\u60a3\u8005\u76845\u5e74\u751f\u5b58\u7387\u63d0\u9ad8\u7d045%<sup>7,8<\/sup>\u3002<\/p>\n\n\n\n<h5 class=\"wp-block-heading\">\u3010\u53c3\u8003\u6587\u737b\u3011<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">1. https:\/\/gco.iarc.fr\/today\/data\/factsheets\/cancers\/15-Lung-fact-sheet.pdf.<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">2. https:\/\/gco.iarc.fr\/today\/data\/factsheets\/populations\/160-china-fact-sheets.pdf.<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">3. Molina JR, et al. Mayo Clin. Proc. 2008; 83(5), 584\u2013594.<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">4. Liang Y, et al.&nbsp; Transl Lung Cancer Res 2013;2:403-10.<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">5. Uramoto H, et al. Transl Lung Cancer Res 2014;3:242-9.<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">6. Taylor MD, et al. Ann Thorac Surg 2012;93:1813-20.<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">7. Pignon JP, et al. J Clin Oncol 2008; 26:3552-3559.<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">8. NSCLC Meta-analysis Collaborative Group. Lancet&nbsp; 2014 ;383(9928):1561-71.<\/h5>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>\u95dc\u65bc\u7279\u745e\u666e\u5229\u55ae\u6297\u6ce8\u5c04\u6db2\uff08\u62d3\u76ca<\/strong><strong><sup>\u00ae<\/sup><\/strong><strong>\uff09<\/strong><strong><\/strong><\/p>\n\n\n\n<p>\u7279\u745e\u666e\u5229\u55ae\u6297\u6ce8\u5c04\u6db2\uff08\u62d3\u76ca<sup>\u00ae<\/sup>\uff09\u4f5c\u70ba\u6211\u570b\u6279\u51c6\u4e0a\u5e02\u7684\u9996\u500b\u570b\u7522\u4ee5PD-1\u70ba\u9776\u9ede\u7684\u55ae\u6297\u85e5\u7269\uff0c\u7372\u5f97\u570b\u5bb6\u79d1\u6280\u91cd\u5927\u5c08\u9805\u5c08\u6848\u652f\u6301\uff0c\u4e26\u69ae\u81ba\u570b\u5bb6\u5c08\u5229\u9818\u57df\u6700\u9ad8\u734e\u9805\u201c\u4e2d\u570b\u5c08\u5229\u91d1\u734e\u201d\u3002<\/p>\n\n\n\n<p>\u7279\u745e\u666e\u5229\u55ae\u6297\u81f3\u4eca\u5df2\u5728\u5168\u7403\uff08\u5305\u62ec\u4e2d\u570b\u3001\u7f8e\u570b\u3001\u6771\u5357\u4e9e\u53ca\u6b50\u6d32\u7b49\u5730\uff09\u958b\u5c55\u4e86\u8986\u84cb\u8d85\u904e15\u500b\u9069\u61c9\u75c7\u768440\u591a\u9805\u7531\u516c\u53f8\u767c\u8d77\u7684\u81e8\u5e8a\u7814\u7a76\u3002\u6b63\u5728\u9032\u884c\u6216\u5df2\u5b8c\u6210\u7684\u95dc\u9375\u8a3b\u518a\u81e8\u5e8a\u7814\u7a76\u5728\u591a\u500b\u7624\u7a2e\u7bc4\u570d\u5167\u8a55\u4f30\u7279\u745e\u666e\u5229\u55ae\u6297\u7684\u5b89\u5168\u6027\u53ca\u7642\u6548\uff0c\u5305\u62ec\u80ba\u764c\u3001\u9f3b\u54bd\u764c\u3001\u98df\u7ba1\u764c\u3001\u80c3\u764c\u3001\u8180\u80f1\u764c\u3001\u4e73\u817a\u764c\u3001\u809d\u764c\u3001\u814e\u764c\u53ca\u76ae\u819a\u764c\u7b49\u3002<\/p>\n\n\n\n<p>\u622a\u81f3\u76ee\u524d\uff0c\u7279\u745e\u666e\u5229\u55ae\u6297\u5df2\u5728\u4e2d\u570b\u7372\u62796\u9805\u9069\u61c9\u75c7\uff1a\u7528\u65bc\u65e2\u5f80\u63a5\u53d7\u5168\u8eab\u7cfb\u7d71\u6cbb\u7642\u5931\u6557\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f49\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u7684\u6cbb\u7642\uff082018\u5e7412\u6708\uff09\uff1b\u7528\u65bc\u65e2\u5f80\u63a5\u53d7\u904e\u4e8c\u7dda\u53ca\u4ee5\u4e0a\u7cfb\u7d71\u6cbb\u7642\u5931\u6557\u7684\u5fa9\u767c\/\u8f49\u79fb\u6027\u9f3b\u54bd\u764c\u60a3\u8005\u7684\u6cbb\u7642\uff082021\u5e742\u6708\uff09\uff1b\u7528\u65bc\u542b\u9251\u5316\u7642\u5931\u6557\u5305\u62ec\u65b0\u8f14\u52a9\u6216\u8f14\u52a9\u5316\u764212\u500b\u6708\u5167\u9032\u5c55\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027\u5c3f\u8def\u4e0a\u76ae\u764c\u7684\u6cbb\u7642\uff082021\u5e744\u6708\uff09\uff1b\u806f\u5408\u9806\u9251\u548c\u5409\u897f\u4ed6\u6ff1\u7528\u65bc\u5c40\u90e8\u5fa9\u767c\u6216\u8f49\u79fb\u6027\u9f3b\u54bd\u764c\u60a3\u8005\u7684\u4e00\u7dda\u6cbb\u7642\uff082021\u5e7411\u6708\uff09\uff1b\u806f\u5408\u7d2b\u6749\u9187\u548c\u9806\u9251\u7528\u65bc\u4e0d\u53ef\u5207\u9664\u5c40\u90e8\u665a\u671f\/\u5fa9\u767c\u6216\u9060\u8655\u8f49\u79fb\u6027\u98df\u7ba1\u9c57\u764c\u60a3\u8005\u7684\u4e00\u7dda\u6cbb\u7642\uff082022\u5e745\u6708\uff09\uff1b\u806f\u5408\u57f9\u7f8e\u66f2\u585e\u548c\u9251\u985e\u7528\u65bc\u8868\u76ae\u751f\u9577\u56e0\u6578\u53d7\u9ad4\uff08EGFR\uff09\u57fa\u56e0\u7a81\u8b8a\u9670\u6027\u548c\u9593\u8b8a\u6027\u6dcb\u5df4\u7624\u6fc0\u9176\uff08ALK\uff09\u9670\u6027\u3001\u4e0d\u53ef\u624b\u8853\u5207\u9664\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027\u975e\u9c57\u72c0\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u7684\u4e00\u7dda\u6cbb\u7642\uff082022\u5e749\u6708\uff09\u30022020\u5e7412\u6708\uff0c\u7279\u745e\u666e\u5229\u55ae\u6297\u9996\u6b21\u901a\u904e\u570b\u5bb6\u91ab\u4fdd\u8ac7\u5224\uff0c\u76ee\u524d\u5df2\u67093\u9805\u9069\u61c9\u75c7\u7d0d\u5165\u300a2022\u5e74\u85e5\u54c1\u76ee\u9304\u300b\uff0c\u662f\u570b\u5bb6\u91ab\u4fdd\u76ee\u9304\u4e2d\u552f\u4e00\u7528\u65bc\u6cbb\u7642\u9ed1\u8272\u7d20\u7624\u7684\u6297PD-1\u55ae\u6297\u85e5\u7269\u3002<\/p>\n\n\n\n<p>\u5728\u570b\u969b\u5316\u4f48\u5c40\u65b9\u9762\uff0c\u7279\u745e\u666e\u5229\u55ae\u6297\u5df2\u5728\u9ecf\u819c\u9ed1\u8272\u7d20\u7624\u3001\u9f3b\u54bd\u764c\u3001\u8edf\u7d44\u7e54\u8089\u7624\u3001\u98df\u7ba1\u764c\u3001\u5c0f\u7d30\u80de\u80ba\u764c\u9818\u57df\u7372\u5f97\u7f8e\u570b\u98df\u54c1\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6388\u4e882\u9805\u7a81\u7834\u6027\u7642\u6cd5\u8a8d\u5b9a\u30011\u9805\u5feb\u901f\u901a\u9053\u8a8d\u5b9a\u30011\u9805\u512a\u5148\u5be9\u8a55\u8a8d\u5b9a\u548c5\u9805\u5b64\u5152\u85e5\u8cc7\u683c\u8a8d\u5b9a\u3002 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Plenary Series\uff094\u6708\u6703\u8b70\u4e0a\u9032\u884c\u4e86\u5168\u7403\u9996\u767c\u516c\u4f48\u3002\u7814\u7a76\u8b49\u5be6\uff0c\u76f8\u8f03\u55ae\u7d14\u5316\u7642\uff0c\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u7528\u65bc\u53ef\u624b\u8853III\u671fNSCLC\u570d\u624b\u8853\u671f\u6cbb\u7642\u53ef\u986f\u8457\u5ef6\u9577\u60a3\u8005\u7684\u7121\u4e8b\u4ef6\u751f\u5b58\u671f\uff08EFS\uff09\uff0c\u63d0\u5347\u4e3b\u8981\u75c5\u7406\u7de9\u89e3\uff08MPR\uff09\u7387\u548c\u5b8c\u5168\u75c5\u7406\u7de9\u89e3\uff08pCR\uff09\u7387\uff0c\u4e26\u4e14\u66f4\u591a\u60a3\u8005\u53ef\u901a\u904e\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u6cbb\u7642\u7372\u5f97\u6839\u6cbb\u6027\u624b\u8853\u7684\u6a5f<\/p>\n","protected":false},"author":3,"featured_media":2153,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[21],"tags":[],"class_list":["post-2156","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-21"],"yoast_head":"\n<title>\u541b\u5be6\u751f\u7269\u9996\u6b21\u516c\u4f48\u7279\u745e\u666e\u5229\u55ae\u6297\u570d\u624b\u8853\u671f\u6cbb\u7642\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u7684\u4e09\u671f\u7814\u7a76\u8cc7\u6599\uff0c\u75be\u75c5\u5fa9\u767c\u3001\u9032\u5c55\u6216\u6b7b\u4ea1\u98a8\u96aa\u964d\u4f4e\u905460% 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content=\"\u5317\u4eac\u6642\u95932023\u5e744\u670821\u65e5\uff0c\u541b\u5be6\u751f\u7269\uff081877.HK\uff0c688180.SH\uff09\u5ba3\u4f48\uff0c\u7531\u516c\u53f8\u81ea\u4e3b\u7814\u767c\u7684\u6297PD-1\u55ae\u6297\u85e5\u7269\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u7528\u65bc\u53ef\u624b\u8853\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u570d\u624b\u8853\u671f\u6cbb\u7642III\u671f\u81e8\u5e8a\u7814\u7a76\uff08Neotorch\uff09\u6210\u679c\u4ee5\u53e3\u982d\u5831\u544a\u5f62\u5f0f\u5728\u7f8e\u570b\u81e8\u5e8a\u816b\u7624\u5b78\u6703\u5168\u9ad4\u5927\u6703\u7cfb\u5217\uff08ASCO Plenary 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